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Tang, A.S.P., et al., Glucagon-like peptide-1 receptor agonist in myocardial infarction and atherosclerotic cardiovascular disease risk reduction: a comprehensive meta-analysis of number needed to treat, efficacy and safety

It is a primary condition for which GLP-1 weight loss injections are approved, due to their effects on insulin and blood sugar levels

Glutathione oxidizes it to dehydroascorbic acid, which is then reduced back to ascorbic acid

119, no

Recent work reveals that GPX4-controlled ferroptosis in neutrophils drives systemic autoimmunity by unleashing redox-active iron, which amplifies inflammatory and immune activation, a hallmark of SLE (216)